Puig, Lluis Guerra-Tapia, Aurora Conejo-Mir, Julián Toribio, Jaime Berasategui, Carmen Zsolt, Ilonka Validation of the Spanish Acne Severity Scale (Escala de Gravedad del Acné Española- EGAE).  The tool ega_download_streamer is available in the Galaxy tool shed: ega_download_streamer. This tool will allow a user within the browser to run an entire analysis containing sensitive data from EGA, and to make this analysis available for other researchers in a reproducible manner, as shown with a proof of concept study. More specifically, we developed a tool - ega_download_streamer - that can download data securely from EGA into a Galaxy server, which can subsequently be further processed. Galaxy provides an intuitive user interface for molecular biologists and bioinformaticians to run and design data analysis workflows. Here we present the first outcomes of this project, a framework to enable the download of EGA data to a Galaxy server in a secure way. As part of this project, a full ecosystem was designed to connect archived raw experimental molecular profiling data with interpreted data and the computational workflows, using the CTMM Translational Research IT (CTMM-TraIT infrastructure as an example. ELIXIR, a European research infrastructure for life-science data, initiated a project (2016 Human Data Implementation Study to understand and document the ELIXIR requirements for secure management of controlled-access data. Moreover, the transfer of data during upload and download is encrypted. Each data provider is responsible for ensuring a Data Access Committee is in place to grant access to data stored in the EGA. The European Genome-phenome Archive ( EGA was created to facilitate access and management to long-term archival of bio-molecular data. Secure access controlled systems are needed to manage, store, transfer and distribute these data due to its personally identifiable nature. Integration of EGA secure data access into Galaxy [version 1 referees: 2 approvedĭirectory of Open Access Journals (Sweden)įull Text Available High-throughput molecular profiling techniques are routinely generating vast amounts of data for translational medicine studies. As part of this project, a full ecosystem was designed to connect archived raw experimental molecular profiling data with interpreted data and the computational workflows, using the CTMM Translational Research IT (CTMM-TraIT) infrastructure as an example. ELIXIR, a European research infrastructure for life-science data, initiated a project (2016 Human Data Implementation Study) to understand and document the ELIXIR requirements for secure management of controlled-access data. The European Genome-phenome Archive ( EGA) was created to facilitate access and management to long-term archival of bio-molecular data. High-throughput molecular profiling techniques are routinely generating vast amounts of data for translational medicine studies. Hoogstrate, Youri Zhang, Chao Senf, Alexander Bijlard, Jochem Hiltemann, Saskia van Enckevort, David Repo, Susanna Heringa, Jaap Jenster, Guido J A Fijneman, Remond Boiten, Jan-Willem A Meijer, Gerrit Stubbs, Andrew Rambla, Jordi Spalding, Dylan Abeln, Sanne Integration of EGA secure data access into Galaxy.
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